E
Epigenuity®
LLC
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Founded by an NIH-funded physician-scientist · Tucson, AZ

Clinical research,
translated into care.

Epigenuity is a physician-scientist-founded research company developing decision-support software and diagnostic platforms across maternal health, oncology, and acute care.

6
Active programs
3+
Provisional patents
1
In-market product
Our thesis
"The hardest problems in medicine aren't in the lab — they're in the workflow gap between evidence and bedside. We build the bridge."
Ravi Goyal, MD, PhD, MBA, FAHA
Scientific Founder · Physician-scientist
Flagship Program
NICHD STTR · in preparation

Serum glycodelin (PAEP) CLIA LDT + EndoTwin-W decision support for frozen embryo transfer timing.

Prospective validation of a serum glycodelin (PAEP) clinical laboratory-developed test paired with the EndoTwin-W computational model, for personalized timing of frozen embryo transfer in IVF cycles. CLIA/CAP laboratory partner and validation IVF clinics in development.

NICHD STTR Fast Track (in preparation) CLIA/CAP laboratory partner in development University of Arizona · research institution endotwin-w.com ↗

Investigational research-use only. Not FDA-cleared. CLIA LDT in development.

Pipeline

Six active programs

Across decision-support software, diagnostics, devices, and computational platforms. Programs are at different stages — from in-market product (PPHrisk) to preclinical (Cas13 liquid biopsy) to validated computational models (EndoTwin-W).

Program
Stage
Smart Pessary
Biofeedback-enabled pessary for pelvic organ prolapse
POP, incontinence
Provisional patent
Preclinical · prototype development
UA licensing in negotiation
Cas13 Liquid Biopsy
CRISPR-Cas13a plasma miRNA assay for early breast cancer detection
Breast cancer screening
Provisional filed
Preclinical proof-of-concept
Future STTR target (NCI)
PPHrisk In market
Postpartum hemorrhage decision support + Maternal Safety Suite
L&D safety
Trade secret + brand
Commercial / Team Edition in early access
EndoTwin-W Platform live
Multiscale digital twin of endometrial receptivity for IVF / women's health
  • • Serum E2 / P4 / glycodelin (PAEP) workflow
  • • 531-sample validation across 13 transcriptomic datasets
  • • Preprint: bioRxiv 2026 →
  • • CLIA LDT in development
Reproductive medicine
Patent pending
v4.0 · Investigational pilot · CLIA LDT in development
NICHD STTR Fast Track in preparation
Critical-care monitoring device
Details under NDA
Acute care
Provisional patent
Prototype + commercialization
Seeking strategic partner
Single-Photon Luminometer
Point-of-care lateral flow reader for low-cost diagnostics
POC diagnostics
Trade secret
Functional prototype
Internal R&D platform

Stage indicators are directional. Summary validation data for EndoTwin-W is public via endotwin-w.com and bioRxiv. Selected technical details for other programs available to partners under CDA.

Approach

Built by a physician-scientist, for clinical reality.

Every Epigenuity program starts with a workflow problem observed at the bedside, not a technology looking for an application. We validate clinically before we engineer commercially.

1

Workflow-first

Programs originate from real clinical gaps — bundle non-compliance, missed early AKI, late-detected breast cancer. We solve what hurts.

2

Translational rigor

In-house bench science (Cas13, RT-RPA, bioimpedance) paired with ovine and human validation. Phase-gated development.

3

Commercialization clarity

Every program has a defined go-to-market path: 510(k), LDT, software, or strategic licensing. No moonshots without a path to patients.

Team

Physician-scientist-founded. Translational by design.

Practicing physicians and scientists with a track record in translational research.

RG
Scientific Founder & CEO

Ravi Goyal, MD, PhD, MBA, FAHA

Vice Chair of Research, OB/GYN · Tenured Professor · University of Arizona College of Medicine

NIH-funded physician-scientist with $14M+ in PI funding across NICHD, NHLBI, and NIEHS portfolios. Vice Chair of Research in the Department of Obstetrics and Gynecology at the University of Arizona, with active R01s in maternal-fetal cerebrovascular biology and developmental epigenetics. Founded Epigenuity to translate workflow insights from L&D and the ICU into deployable decision-support and diagnostic products.

$14M+ NIH PI funding Active R01s · NICHD, NHLBI Fellow, American Heart Association (FAHA) AHA / NIH study section reviewer 55+ peer-reviewed publications MD, PhD, MBA, FAHA
Scientific Advisory Board

We're assembling an SAB with deep expertise in maternal-fetal medicine, oncology, and digital health.

Interested in advising? →
Collaborators

Active collaborations with the University of Arizona, Banner Health, and clinical partners across the Southwest.

Open to new partnerships →
Funding & Partnerships

Federal research strategy and institutional partners.

Across six active programs, Epigenuity is preparing federal STTR / SBIR applications, formalizing institutional partnerships, and filing IP. Summary validation data is public for EndoTwin-W; selected technical details available to qualified partners under CDA.

Flagship STTR

NICHD · Glycodelin + EndoTwin-W

STTR Fast Track in preparation for serum glycodelin (PAEP) CLIA laboratory-developed test paired with EndoTwin-W decision support for frozen embryo transfer timing. Prospective IVF clinic validation in design phase.

In preparation
NICHD · Fast Track
Institutional Partner

University of Arizona

University of Arizona as research institution partner. Active engagement with UA Tech Launch Arizona (TLA) regarding licensing of inventions developed under university affiliation. Licensing in negotiation.

Active
Research partner
Clinical Lab Pathway

CLIA/CAP partner in development

Identifying and engaging a CLIA/CAP-certified clinical laboratory partner for the serum glycodelin (PAEP) laboratory-developed test underlying the EndoTwin-W assay workflow. Discussions in progress.

In development
CLIA LDT pathway
Commercial Traction

PPHrisk in market

Decision-support software with 30-day free trial, individual subscriptions, and L&D Team Edition in early access. EndoTwin-W computational platform live at endotwin-w.com. Two of six programs already in market.

2 live
IP Portfolio

Provisional patents filed

Active provisional applications covering EndoTwin-W methodology, Smart Pessary technology, critical-care monitoring, and assay platform design. Non-provisional conversions in progress.

3+
Active filings
Founder Track Record

$14M+ NIH funding as PI

Founder Dr. Ravi Goyal (MD, PhD, MBA, FAHA) has a decade-plus history of NIH funding across NICHD, NHLBI, and NIEHS portfolios, including active R01 awards. AHA Fellow, study section reviewer (15+ AHA panels, 4+ NIH committees). Vice Chair of Research, UA OB/GYN.

Active R01s

Selected technical details available to qualified partners under CDA. Summary validation data on EndoTwin-W is available at endotwin-w.com and bioRxiv.

Publications & Research

55+ peer-reviewed publications.

Founder bibliography spans maternal-fetal physiology, vascular biology, IUGR, developmental epigenetics, traumatic brain injury, and translational medicine — including a 94-page review in Physiological Reviews (2018).

View full PubMed bibliography (55 publications)
Ravi Goyal · My NCBI · spanning 2007–2023
Get in touch

Multiple ways to engage.

Whether you're a clinical collaborator, investor, prospective hire, advisor, or someone from a federal agency or foundation — we want to hear from you.

Epigenuity LLC · Tucson, Arizona · United States